KSM-66 is a high-concentration, full-spectrum root extract of ashwagandha, standardized to ≥5% withanolides. It is produced using a solvent-free extraction process that preserves the herb’s natural balance of bioactive compounds.
Unlike many extracts that use both leaf and root, KSM-66 uses root-only extract, which aligns with traditional Ayurvedic use and may offer better tolerability.
Functions:
Helps regulate the hypothalamic–pituitary–adrenal (HPA) axis
Reduces elevated cortisol levels
Supports GABAergic activity for calm and sleep
Enhances mitochondrial function and endurance
May support healthy testosterone levels in men
Provides antioxidant and anti-inflammatory effects
TAILORBLEND uses KSM-66 for its strong clinical backing, standardized potency, and consistent bioavailability
KSM-66® Ashwagandha is a clinically studied full-spectrum root extract of Withania somnifera, commonly used to support:
Stress reduction and cortisol balance
Anxiety resilience and mood stability
Improved sleep quality
Physical performance and muscle recovery
Testosterone support and male fertility
Cognitive function and focus
Thyroid support (particularly in subclinical hypothyroidism)
Ashwagandha is a medicinal root and not naturally present in common foods.
Synergistic Nutrients:
Magnesium: supports relaxation and sleep
L-theanine: promotes calm focus
Rhodiola rosea: complements stress resilience
Zinc: supports testosterone and immune function
B-complex vitamins: support stress metabolism
Typical Dosages:
General stress support: 100 mg/day
Moderate stress or performance support: 300 mg twice daily (600 mg/day)
Sleep support: 300–600 mg in the evening
Common Cycling Protocols:
Avoid use during pregnancy unless under medical supervision
Use caution in hyperthyroidism (may increase thyroid hormone levels)
May enhance effects of sedatives or anti-anxiety medication
Consult a healthcare provider if managing autoimmune disease, thyroid conditions, or psychiatric disorders
Lopresti et al., Medicine (Baltimore) (2019) – Ashwagandha and cortisol reduction
Wankhede et al., J Int Soc Sports Nutr (2015) – Ashwagandha and strength/performance
Sharma et al., J Ethnopharmacol (2018) – Ashwagandha and thyroid function